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Dec 8

Segmentation with Noisy Labels via Spatially Correlated Distributions

In semantic segmentation, the accuracy of models heavily depends on the high-quality annotations. However, in many practical scenarios such as medical imaging and remote sensing, obtaining true annotations is not straightforward and usually requires significant human labor. Relying on human labor often introduces annotation errors, including mislabeling, omissions, and inconsistency between annotators. In the case of remote sensing, differences in procurement time can lead to misaligned ground truth annotations. These label errors are not independently distributed, and instead usually appear in spatially connected regions where adjacent pixels are more likely to share the same errors. To address these issues, we propose an approximate Bayesian estimation based on a probabilistic model that assumes training data includes label errors, incorporating the tendency for these errors to occur with spatial correlations between adjacent pixels. Bayesian inference requires computing the posterior distribution of label errors, which becomes intractable when spatial correlations are present. We represent the correlation of label errors between adjacent pixels through a Gaussian distribution whose covariance is structured by a Kac-Murdock-Szeg\"{o} (KMS) matrix, solving the computational challenges. Through experiments on multiple segmentation tasks, we confirm that leveraging the spatial correlation of label errors significantly improves performance. Notably, in specific tasks such as lung segmentation, the proposed method achieves performance comparable to training with clean labels under moderate noise levels. Code is available at https://github.com/pfnet-research/Bayesian_SpatialCorr.

  • 3 authors
·
Apr 20

Hierarchical multi-class segmentation of glioma images using networks with multi-level activation function

For many segmentation tasks, especially for the biomedical image, the topological prior is vital information which is useful to exploit. The containment/nesting is a typical inter-class geometric relationship. In the MICCAI Brain tumor segmentation challenge, with its three hierarchically nested classes 'whole tumor', 'tumor core', 'active tumor', the nested classes relationship is introduced into the 3D-residual-Unet architecture. The network comprises a context aggregation pathway and a localization pathway, which encodes increasingly abstract representation of the input as going deeper into the network, and then recombines these representations with shallower features to precisely localize the interest domain via a localization path. The nested-class-prior is combined by proposing the multi-class activation function and its corresponding loss function. The model is trained on the training dataset of Brats2018, and 20% of the dataset is regarded as the validation dataset to determine parameters. When the parameters are fixed, we retrain the model on the whole training dataset. The performance achieved on the validation leaderboard is 86%, 77% and 72% Dice scores for the whole tumor, enhancing tumor and tumor core classes without relying on ensembles or complicated post-processing steps. Based on the same start-of-the-art network architecture, the accuracy of nested-class (enhancing tumor) is reasonably improved from 69% to 72% compared with the traditional Softmax-based method which blind to topological prior.

  • 6 authors
·
Oct 22, 2018

TransUNet: Transformers Make Strong Encoders for Medical Image Segmentation

Medical image segmentation is an essential prerequisite for developing healthcare systems, especially for disease diagnosis and treatment planning. On various medical image segmentation tasks, the u-shaped architecture, also known as U-Net, has become the de-facto standard and achieved tremendous success. However, due to the intrinsic locality of convolution operations, U-Net generally demonstrates limitations in explicitly modeling long-range dependency. Transformers, designed for sequence-to-sequence prediction, have emerged as alternative architectures with innate global self-attention mechanisms, but can result in limited localization abilities due to insufficient low-level details. In this paper, we propose TransUNet, which merits both Transformers and U-Net, as a strong alternative for medical image segmentation. On one hand, the Transformer encodes tokenized image patches from a convolution neural network (CNN) feature map as the input sequence for extracting global contexts. On the other hand, the decoder upsamples the encoded features which are then combined with the high-resolution CNN feature maps to enable precise localization. We argue that Transformers can serve as strong encoders for medical image segmentation tasks, with the combination of U-Net to enhance finer details by recovering localized spatial information. TransUNet achieves superior performances to various competing methods on different medical applications including multi-organ segmentation and cardiac segmentation. Code and models are available at https://github.com/Beckschen/TransUNet.

  • 9 authors
·
Feb 8, 2021

Barlow-Swin: Toward a novel siamese-based segmentation architecture using Swin-Transformers

Medical image segmentation is a critical task in clinical workflows, particularly for the detection and delineation of pathological regions. While convolutional architectures like U-Net have become standard for such tasks, their limited receptive field restricts global context modeling. Recent efforts integrating transformers have addressed this, but often result in deep, computationally expensive models unsuitable for real-time use. In this work, we present a novel end-to-end lightweight architecture designed specifically for real-time binary medical image segmentation. Our model combines a Swin Transformer-like encoder with a U-Net-like decoder, connected via skip pathways to preserve spatial detail while capturing contextual information. Unlike existing designs such as Swin Transformer or U-Net, our architecture is significantly shallower and competitively efficient. To improve the encoder's ability to learn meaningful features without relying on large amounts of labeled data, we first train it using Barlow Twins, a self-supervised learning method that helps the model focus on important patterns by reducing unnecessary repetition in the learned features. After this pretraining, we fine-tune the entire model for our specific task. Experiments on benchmark binary segmentation tasks demonstrate that our model achieves competitive accuracy with substantially reduced parameter count and faster inference, positioning it as a practical alternative for deployment in real-time and resource-limited clinical environments. The code for our method is available at Github repository: https://github.com/mkianih/Barlow-Swin.

  • 5 authors
·
Sep 8

Adapting Pre-Trained Vision Models for Novel Instance Detection and Segmentation

Novel Instance Detection and Segmentation (NIDS) aims at detecting and segmenting novel object instances given a few examples of each instance. We propose a unified, simple, yet effective framework (NIDS-Net) comprising object proposal generation, embedding creation for both instance templates and proposal regions, and embedding matching for instance label assignment. Leveraging recent advancements in large vision methods, we utilize Grounding DINO and Segment Anything Model (SAM) to obtain object proposals with accurate bounding boxes and masks. Central to our approach is the generation of high-quality instance embeddings. We utilized foreground feature averages of patch embeddings from the DINOv2 ViT backbone, followed by refinement through a weight adapter mechanism that we introduce. We show experimentally that our weight adapter can adjust the embeddings locally within their feature space and effectively limit overfitting in the few-shot setting. Furthermore, the weight adapter optimizes weights to enhance the distinctiveness of instance embeddings during similarity computation. This methodology enables a straightforward matching strategy that results in significant performance gains. Our framework surpasses current state-of-the-art methods, demonstrating notable improvements in four detection datasets. In the segmentation tasks on seven core datasets of the BOP challenge, our method outperforms the leading published RGB methods and remains competitive with the best RGB-D method. We have also verified our method using real-world images from a Fetch robot and a RealSense camera. Project Page: https://irvlutd.github.io/NIDSNet/

  • 5 authors
·
May 28, 2024

Interactive Medical Image Segmentation: A Benchmark Dataset and Baseline

Interactive Medical Image Segmentation (IMIS) has long been constrained by the limited availability of large-scale, diverse, and densely annotated datasets, which hinders model generalization and consistent evaluation across different models. In this paper, we introduce the IMed-361M benchmark dataset, a significant advancement in general IMIS research. First, we collect and standardize over 6.4 million medical images and their corresponding ground truth masks from multiple data sources. Then, leveraging the strong object recognition capabilities of a vision foundational model, we automatically generated dense interactive masks for each image and ensured their quality through rigorous quality control and granularity management. Unlike previous datasets, which are limited by specific modalities or sparse annotations, IMed-361M spans 14 modalities and 204 segmentation targets, totaling 361 million masks-an average of 56 masks per image. Finally, we developed an IMIS baseline network on this dataset that supports high-quality mask generation through interactive inputs, including clicks, bounding boxes, text prompts, and their combinations. We evaluate its performance on medical image segmentation tasks from multiple perspectives, demonstrating superior accuracy and scalability compared to existing interactive segmentation models. To facilitate research on foundational models in medical computer vision, we release the IMed-361M and model at https://github.com/uni-medical/IMIS-Bench.

  • 13 authors
·
Nov 19, 2024 2

Unsupervised Universal Image Segmentation

Several unsupervised image segmentation approaches have been proposed which eliminate the need for dense manually-annotated segmentation masks; current models separately handle either semantic segmentation (e.g., STEGO) or class-agnostic instance segmentation (e.g., CutLER), but not both (i.e., panoptic segmentation). We propose an Unsupervised Universal Segmentation model (U2Seg) adept at performing various image segmentation tasks -- instance, semantic and panoptic -- using a novel unified framework. U2Seg generates pseudo semantic labels for these segmentation tasks via leveraging self-supervised models followed by clustering; each cluster represents different semantic and/or instance membership of pixels. We then self-train the model on these pseudo semantic labels, yielding substantial performance gains over specialized methods tailored to each task: a +2.6 AP^{box} boost vs. CutLER in unsupervised instance segmentation on COCO and a +7.0 PixelAcc increase (vs. STEGO) in unsupervised semantic segmentation on COCOStuff. Moreover, our method sets up a new baseline for unsupervised panoptic segmentation, which has not been previously explored. U2Seg is also a strong pretrained model for few-shot segmentation, surpassing CutLER by +5.0 AP^{mask} when trained on a low-data regime, e.g., only 1% COCO labels. We hope our simple yet effective method can inspire more research on unsupervised universal image segmentation.

  • 6 authors
·
Dec 28, 2023 2

MedSegDiff: Medical Image Segmentation with Diffusion Probabilistic Model

Diffusion probabilistic model (DPM) recently becomes one of the hottest topic in computer vision. Its image generation application such as Imagen, Latent Diffusion Models and Stable Diffusion have shown impressive generation capabilities, which aroused extensive discussion in the community. Many recent studies also found it is useful in many other vision tasks, like image deblurring, super-resolution and anomaly detection. Inspired by the success of DPM, we propose the first DPM based model toward general medical image segmentation tasks, which we named MedSegDiff. In order to enhance the step-wise regional attention in DPM for the medical image segmentation, we propose dynamic conditional encoding, which establishes the state-adaptive conditions for each sampling step. We further propose Feature Frequency Parser (FF-Parser), to eliminate the negative effect of high-frequency noise component in this process. We verify MedSegDiff on three medical segmentation tasks with different image modalities, which are optic cup segmentation over fundus images, brain tumor segmentation over MRI images and thyroid nodule segmentation over ultrasound images. The experimental results show that MedSegDiff outperforms state-of-the-art (SOTA) methods with considerable performance gap, indicating the generalization and effectiveness of the proposed model. Our code is released at https://github.com/WuJunde/MedSegDiff.

  • 8 authors
·
Nov 1, 2022

MedSAMix: A Training-Free Model Merging Approach for Medical Image Segmentation

Universal medical image segmentation models have emerged as a promising paradigm due to their strong generalizability across diverse tasks, showing great potential for a wide range of clinical applications. This potential has been partly driven by the success of general-purpose vision models such as the Segment Anything Model (SAM), which has inspired the development of various fine-tuned variants for medical segmentation tasks. However, fine-tuned variants like MedSAM are trained on comparatively limited medical imaging data that often suffers from heterogeneity, scarce annotations, and distributional shifts. These challenges limit their ability to generalize across a wide range of medical segmentation tasks. In this regard, we propose MedSAMix, a training-free model merging method that integrates the strengths of both generalist models (e.g., SAM) and specialist models (e.g., MedSAM) for medical image segmentation. In contrast to traditional model merging approaches that rely on manual configuration and often result in suboptimal outcomes, we propose a zero-order optimization method to automatically discover optimal layer-wise merging solutions. Furthermore, for clinical applications, we develop two regimes to meet the demand of domain-specificity and generalizability in different scenarios by single-task optimization and multi-objective optimization respectively. Extensive evaluations on 25 medical segmentation tasks demonstrate that MedSAMix effectively mitigates model bias and consistently improves performance in both domain-specific accuracy and generalization, achieving improvements of 6.67% on specialized tasks and 4.37% on multi-task evaluations.

  • 6 authors
·
Aug 14 2

ZS-VCOS: Zero-Shot Video Camouflaged Object Segmentation By Optical Flow and Open Vocabulary Object Detection

Camouflaged object segmentation presents unique challenges compared to traditional segmentation tasks, primarily due to the high similarity in patterns and colors between camouflaged objects and their backgrounds. Effective solutions to this problem have significant implications in critical areas such as pest control, defect detection, and lesion segmentation in medical imaging. Prior research has predominantly emphasized supervised or unsupervised pre-training methods, leaving zero-shot approaches significantly underdeveloped. Existing zero-shot techniques commonly utilize the Segment Anything Model (SAM) in automatic mode or rely on vision-language models to generate cues for segmentation; however, their performances remain unsatisfactory, due to the similarity of the camouflaged object and the background. This work studies how to avoid training by integrating large pre-trained models like SAM-2 and Owl-v2 with temporal information into a modular pipeline. Evaluated on the MoCA-Mask dataset, our approach achieves outstanding performance improvements, significantly outperforming existing zero-shot methods by raising the F-measure (F_beta^w) from 0.296 to 0.628. Our approach also surpasses supervised methods, increasing the F-measure from 0.476 to 0.628. Additionally, evaluation on the MoCA-Filter dataset demonstrates an increase in the success rate from 0.628 to 0.697 when compared with FlowSAM, a supervised transfer method. A thorough ablation study further validates the individual contributions of each component. Besides our main contributions, we also highlight inconsistencies in previous work regarding metrics and settings. Code can be found in https://github.com/weathon/vcos.

  • 3 authors
·
Apr 10

Co-Seg++: Mutual Prompt-Guided Collaborative Learning for Versatile Medical Segmentation

Medical image analysis is critical yet challenged by the need of jointly segmenting organs or tissues, and numerous instances for anatomical structures and tumor microenvironment analysis. Existing studies typically formulated different segmentation tasks in isolation, which overlooks the fundamental interdependencies between these tasks, leading to suboptimal segmentation performance and insufficient medical image understanding. To address this issue, we propose a Co-Seg++ framework for versatile medical segmentation. Specifically, we introduce a novel co-segmentation paradigm, allowing semantic and instance segmentation tasks to mutually enhance each other. We first devise a spatio-temporal prompt encoder (STP-Encoder) to capture long-range spatial and temporal relationships between segmentation regions and image embeddings as prior spatial constraints. Moreover, we devise a multi-task collaborative decoder (MTC-Decoder) that leverages cross-guidance to strengthen the contextual consistency of both tasks, jointly computing semantic and instance segmentation masks. Extensive experiments on diverse CT and histopathology datasets demonstrate that the proposed Co-Seg++ outperforms state-of-the-arts in the semantic, instance, and panoptic segmentation of dental anatomical structures, histopathology tissues, and nuclei instances. The source code is available at https://github.com/xq141839/Co-Seg-Plus.

  • 4 authors
·
Jun 20

DB-SAM: Delving into High Quality Universal Medical Image Segmentation

Recently, the Segment Anything Model (SAM) has demonstrated promising segmentation capabilities in a variety of downstream segmentation tasks. However in the context of universal medical image segmentation there exists a notable performance discrepancy when directly applying SAM due to the domain gap between natural and 2D/3D medical data. In this work, we propose a dual-branch adapted SAM framework, named DB-SAM, that strives to effectively bridge this domain gap. Our dual-branch adapted SAM contains two branches in parallel: a ViT branch and a convolution branch. The ViT branch incorporates a learnable channel attention block after each frozen attention block, which captures domain-specific local features. On the other hand, the convolution branch employs a light-weight convolutional block to extract domain-specific shallow features from the input medical image. To perform cross-branch feature fusion, we design a bilateral cross-attention block and a ViT convolution fusion block, which dynamically combine diverse information of two branches for mask decoder. Extensive experiments on large-scale medical image dataset with various 3D and 2D medical segmentation tasks reveal the merits of our proposed contributions. On 21 3D medical image segmentation tasks, our proposed DB-SAM achieves an absolute gain of 8.8%, compared to a recent medical SAM adapter in the literature. The code and model are available at https://github.com/AlfredQin/DB-SAM.

  • 5 authors
·
Oct 5, 2024

MedCLIP-SAMv2: Towards Universal Text-Driven Medical Image Segmentation

Segmentation of anatomical structures and pathological regions in medical images is essential for modern clinical diagnosis, disease research, and treatment planning. While significant advancements have been made in deep learning-based segmentation techniques, many of these methods still suffer from limitations in data efficiency, generalizability, and interactivity. As a result, developing precise segmentation methods that require fewer labeled datasets remains a critical challenge in medical image analysis. Recently, the introduction of foundation models like CLIP and Segment-Anything-Model (SAM), with robust cross-domain representations, has paved the way for interactive and universal image segmentation. However, further exploration of these models for data-efficient segmentation in medical imaging is still needed and highly relevant. In this paper, we introduce MedCLIP-SAMv2, a novel framework that integrates the CLIP and SAM models to perform segmentation on clinical scans using text prompts, in both zero-shot and weakly supervised settings. Our approach includes fine-tuning the BiomedCLIP model with a new Decoupled Hard Negative Noise Contrastive Estimation (DHN-NCE) loss, and leveraging the Multi-modal Information Bottleneck (M2IB) to create visual prompts for generating segmentation masks from SAM in the zero-shot setting. We also investigate using zero-shot segmentation labels within a weakly supervised paradigm to enhance segmentation quality further. Extensive testing across four diverse segmentation tasks and medical imaging modalities (breast tumor ultrasound, brain tumor MRI, lung X-ray, and lung CT) demonstrates the high accuracy of our proposed framework. Our code is available at https://github.com/HealthX-Lab/MedCLIP-SAMv2.

  • 4 authors
·
Sep 28, 2024

MedCLIP-SAM: Bridging Text and Image Towards Universal Medical Image Segmentation

Medical image segmentation of anatomical structures and pathology is crucial in modern clinical diagnosis, disease study, and treatment planning. To date, great progress has been made in deep learning-based segmentation techniques, but most methods still lack data efficiency, generalizability, and interactability. Consequently, the development of new, precise segmentation methods that demand fewer labeled datasets is of utmost importance in medical image analysis. Recently, the emergence of foundation models, such as CLIP and Segment-Anything-Model (SAM), with comprehensive cross-domain representation opened the door for interactive and universal image segmentation. However, exploration of these models for data-efficient medical image segmentation is still limited, but is highly necessary. In this paper, we propose a novel framework, called MedCLIP-SAM that combines CLIP and SAM models to generate segmentation of clinical scans using text prompts in both zero-shot and weakly supervised settings. To achieve this, we employed a new Decoupled Hard Negative Noise Contrastive Estimation (DHN-NCE) loss to fine-tune the BiomedCLIP model and the recent gScoreCAM to generate prompts to obtain segmentation masks from SAM in a zero-shot setting. Additionally, we explored the use of zero-shot segmentation labels in a weakly supervised paradigm to improve the segmentation quality further. By extensively testing three diverse segmentation tasks and medical image modalities (breast tumor ultrasound, brain tumor MRI, and lung X-ray), our proposed framework has demonstrated excellent accuracy. Code is available at https://github.com/HealthX-Lab/MedCLIP-SAM.

  • 4 authors
·
Mar 29, 2024

Comparing YOLOv8 and Mask RCNN for object segmentation in complex orchard environments

Instance segmentation, an important image processing operation for automation in agriculture, is used to precisely delineate individual objects of interest within images, which provides foundational information for various automated or robotic tasks such as selective harvesting and precision pruning. This study compares the one-stage YOLOv8 and the two-stage Mask R-CNN machine learning models for instance segmentation under varying orchard conditions across two datasets. Dataset 1, collected in dormant season, includes images of dormant apple trees, which were used to train multi-object segmentation models delineating tree branches and trunks. Dataset 2, collected in the early growing season, includes images of apple tree canopies with green foliage and immature (green) apples (also called fruitlet), which were used to train single-object segmentation models delineating only immature green apples. The results showed that YOLOv8 performed better than Mask R-CNN, achieving good precision and near-perfect recall across both datasets at a confidence threshold of 0.5. Specifically, for Dataset 1, YOLOv8 achieved a precision of 0.90 and a recall of 0.95 for all classes. In comparison, Mask R-CNN demonstrated a precision of 0.81 and a recall of 0.81 for the same dataset. With Dataset 2, YOLOv8 achieved a precision of 0.93 and a recall of 0.97. Mask R-CNN, in this single-class scenario, achieved a precision of 0.85 and a recall of 0.88. Additionally, the inference times for YOLOv8 were 10.9 ms for multi-class segmentation (Dataset 1) and 7.8 ms for single-class segmentation (Dataset 2), compared to 15.6 ms and 12.8 ms achieved by Mask R-CNN's, respectively.

  • 3 authors
·
Dec 13, 2023

I-MedSAM: Implicit Medical Image Segmentation with Segment Anything

With the development of Deep Neural Networks (DNNs), many efforts have been made to handle medical image segmentation. Traditional methods such as nnUNet train specific segmentation models on the individual datasets. Plenty of recent methods have been proposed to adapt the foundational Segment Anything Model (SAM) to medical image segmentation. However, they still focus on discrete representations to generate pixel-wise predictions, which are spatially inflexible and scale poorly to higher resolution. In contrast, implicit methods learn continuous representations for segmentation, which is crucial for medical image segmentation. In this paper, we propose I-MedSAM, which leverages the benefits of both continuous representations and SAM, to obtain better cross-domain ability and accurate boundary delineation. Since medical image segmentation needs to predict detailed segmentation boundaries, we designed a novel adapter to enhance the SAM features with high-frequency information during Parameter-Efficient Fine-Tuning (PEFT). To convert the SAM features and coordinates into continuous segmentation output, we utilize Implicit Neural Representation (INR) to learn an implicit segmentation decoder. We also propose an uncertainty-guided sampling strategy for efficient learning of INR. Extensive evaluations on 2D medical image segmentation tasks have shown that our proposed method with only 1.6M trainable parameters outperforms existing methods including discrete and implicit methods. The code will be available at: https://github.com/ucwxb/I-MedSAM.

  • 6 authors
·
Nov 27, 2023

Few-Shot Segmentation Without Meta-Learning: A Good Transductive Inference Is All You Need?

We show that the way inference is performed in few-shot segmentation tasks has a substantial effect on performances -- an aspect often overlooked in the literature in favor of the meta-learning paradigm. We introduce a transductive inference for a given query image, leveraging the statistics of its unlabeled pixels, by optimizing a new loss containing three complementary terms: i) the cross-entropy on the labeled support pixels; ii) the Shannon entropy of the posteriors on the unlabeled query-image pixels; and iii) a global KL-divergence regularizer based on the proportion of the predicted foreground. As our inference uses a simple linear classifier of the extracted features, its computational load is comparable to inductive inference and can be used on top of any base training. Foregoing episodic training and using only standard cross-entropy training on the base classes, our inference yields competitive performances on standard benchmarks in the 1-shot scenarios. As the number of available shots increases, the gap in performances widens: on PASCAL-5i, our method brings about 5% and 6% improvements over the state-of-the-art, in the 5- and 10-shot scenarios, respectively. Furthermore, we introduce a new setting that includes domain shifts, where the base and novel classes are drawn from different datasets. Our method achieves the best performances in this more realistic setting. Our code is freely available online: https://github.com/mboudiaf/RePRI-for-Few-Shot-Segmentation.

  • 6 authors
·
Dec 11, 2020

Bridging 2D and 3D Segmentation Networks for Computation Efficient Volumetric Medical Image Segmentation: An Empirical Study of 2.5D Solutions

Recently, deep convolutional neural networks have achieved great success for medical image segmentation. However, unlike segmentation of natural images, most medical images such as MRI and CT are volumetric data. In order to make full use of volumetric information, 3D CNNs are widely used. However, 3D CNNs suffer from higher inference time and computation cost, which hinders their further clinical applications. Additionally, with the increased number of parameters, the risk of overfitting is higher, especially for medical images where data and annotations are expensive to acquire. To issue this problem, many 2.5D segmentation methods have been proposed to make use of volumetric spatial information with less computation cost. Despite these works lead to improvements on a variety of segmentation tasks, to the best of our knowledge, there has not previously been a large-scale empirical comparison of these methods. In this paper, we aim to present a review of the latest developments of 2.5D methods for volumetric medical image segmentation. Additionally, to compare the performance and effectiveness of these methods, we provide an empirical study of these methods on three representative segmentation tasks involving different modalities and targets. Our experimental results highlight that 3D CNNs may not always be the best choice. Despite all these 2.5D methods can bring performance gains to 2D baseline, not all the methods hold the benefits on different datasets. We hope the results and conclusions of our study will prove useful for the community on exploring and developing efficient volumetric medical image segmentation methods.

  • 4 authors
·
Oct 13, 2020

Recurrent Residual Convolutional Neural Network based on U-Net (R2U-Net) for Medical Image Segmentation

Deep learning (DL) based semantic segmentation methods have been providing state-of-the-art performance in the last few years. More specifically, these techniques have been successfully applied to medical image classification, segmentation, and detection tasks. One deep learning technique, U-Net, has become one of the most popular for these applications. In this paper, we propose a Recurrent Convolutional Neural Network (RCNN) based on U-Net as well as a Recurrent Residual Convolutional Neural Network (RRCNN) based on U-Net models, which are named RU-Net and R2U-Net respectively. The proposed models utilize the power of U-Net, Residual Network, as well as RCNN. There are several advantages of these proposed architectures for segmentation tasks. First, a residual unit helps when training deep architecture. Second, feature accumulation with recurrent residual convolutional layers ensures better feature representation for segmentation tasks. Third, it allows us to design better U-Net architecture with same number of network parameters with better performance for medical image segmentation. The proposed models are tested on three benchmark datasets such as blood vessel segmentation in retina images, skin cancer segmentation, and lung lesion segmentation. The experimental results show superior performance on segmentation tasks compared to equivalent models including U-Net and residual U-Net (ResU-Net).

  • 5 authors
·
Feb 19, 2018

Vision-Language Model for Object Detection and Segmentation: A Review and Evaluation

Vision-Language Model (VLM) have gained widespread adoption in Open-Vocabulary (OV) object detection and segmentation tasks. Despite they have shown promise on OV-related tasks, their effectiveness in conventional vision tasks has thus far been unevaluated. In this work, we present the systematic review of VLM-based detection and segmentation, view VLM as the foundational model and conduct comprehensive evaluations across multiple downstream tasks for the first time: 1) The evaluation spans eight detection scenarios (closed-set detection, domain adaptation, crowded objects, etc.) and eight segmentation scenarios (few-shot, open-world, small object, etc.), revealing distinct performance advantages and limitations of various VLM architectures across tasks. 2) As for detection tasks, we evaluate VLMs under three finetuning granularities: zero prediction, visual fine-tuning, and text prompt, and further analyze how different finetuning strategies impact performance under varied task. 3) Based on empirical findings, we provide in-depth analysis of the correlations between task characteristics, model architectures, and training methodologies, offering insights for future VLM design. 4) We believe that this work shall be valuable to the pattern recognition experts working in the fields of computer vision, multimodal learning, and vision foundation models by introducing them to the problem, and familiarizing them with the current status of the progress while providing promising directions for future research. A project associated with this review and evaluation has been created at https://github.com/better-chao/perceptual_abilities_evaluation.

  • 16 authors
·
Apr 13

Instruction-guided Multi-Granularity Segmentation and Captioning with Large Multimodal Model

Large Multimodal Models (LMMs) have achieved significant progress by extending large language models. Building on this progress, the latest developments in LMMs demonstrate the ability to generate dense pixel-wise segmentation through the integration of segmentation models.Despite the innovations, the textual responses and segmentation masks of existing works remain at the instance level, showing limited ability to perform fine-grained understanding and segmentation even provided with detailed textual cues.To overcome this limitation, we introduce a Multi-Granularity Large Multimodal Model (MGLMM), which is capable of seamlessly adjusting the granularity of Segmentation and Captioning (SegCap) following user instructions, from panoptic SegCap to fine-grained SegCap. We name such a new task Multi-Granularity Segmentation and Captioning (MGSC). Observing the lack of a benchmark for model training and evaluation over the MGSC task, we establish a benchmark with aligned masks and captions in multi-granularity using our customized automated annotation pipeline. This benchmark comprises 10K images and more than 30K image-question pairs. We will release our dataset along with the implementation of our automated dataset annotation pipeline for further research.Besides, we propose a novel unified SegCap data format to unify heterogeneous segmentation datasets; it effectively facilitates learning to associate object concepts with visual features during multi-task training. Extensive experiments demonstrate that our MGLMM excels at tackling more than eight downstream tasks and achieves state-of-the-art performance in MGSC, GCG, image captioning, referring segmentation, multiple and empty segmentation, and reasoning segmentation tasks. The great performance and versatility of MGLMM underscore its potential impact on advancing multimodal research.

  • 5 authors
·
Sep 20, 2024 2

CromSS: Cross-modal pre-training with noisy labels for remote sensing image segmentation

We explore the potential of large-scale noisily labeled data to enhance feature learning by pretraining semantic segmentation models within a multi-modal framework for geospatial applications. We propose a novel Cross-modal Sample Selection (CromSS) method, a weakly supervised pretraining strategy designed to improve feature representations through cross-modal consistency and noise mitigation techniques. Unlike conventional pretraining approaches, CromSS exploits massive amounts of noisy and easy-to-come-by labels for improved feature learning beneficial to semantic segmentation tasks. We investigate middle and late fusion strategies to optimize the multi-modal pretraining architecture design. We also introduce a cross-modal sample selection module to mitigate the adverse effects of label noise, which employs a cross-modal entangling strategy to refine the estimated confidence masks within each modality to guide the sampling process. Additionally, we introduce a spatial-temporal label smoothing technique to counteract overconfidence for enhanced robustness against noisy labels. To validate our approach, we assembled the multi-modal dataset, NoLDO-S12, which consists of a large-scale noisy label subset from Google's Dynamic World (DW) dataset for pretraining and two downstream subsets with high-quality labels from Google DW and OpenStreetMap (OSM) for transfer learning. Experimental results on two downstream tasks and the publicly available DFC2020 dataset demonstrate that when effectively utilized, the low-cost noisy labels can significantly enhance feature learning for segmentation tasks. All data, code, and pretrained weights will be made publicly available.

  • 4 authors
·
May 2, 2024

ConnNet: A Long-Range Relation-Aware Pixel-Connectivity Network for Salient Segmentation

Salient segmentation aims to segment out attention-grabbing regions, a critical yet challenging task and the foundation of many high-level computer vision applications. It requires semantic-aware grouping of pixels into salient regions and benefits from the utilization of global multi-scale contexts to achieve good local reasoning. Previous works often address it as two-class segmentation problems utilizing complicated multi-step procedures including refinement networks and complex graphical models. We argue that semantic salient segmentation can instead be effectively resolved by reformulating it as a simple yet intuitive pixel-pair based connectivity prediction task. Following the intuition that salient objects can be naturally grouped via semantic-aware connectivity between neighboring pixels, we propose a pure Connectivity Net (ConnNet). ConnNet predicts connectivity probabilities of each pixel with its neighboring pixels by leveraging multi-level cascade contexts embedded in the image and long-range pixel relations. We investigate our approach on two tasks, namely salient object segmentation and salient instance-level segmentation, and illustrate that consistent improvements can be obtained by modeling these tasks as connectivity instead of binary segmentation tasks for a variety of network architectures. We achieve state-of-the-art performance, outperforming or being comparable to existing approaches while reducing inference time due to our less complex approach.

  • 5 authors
·
Apr 20, 2018

When Semantic Segmentation Meets Frequency Aliasing

Despite recent advancements in semantic segmentation, where and what pixels are hard to segment remains largely unexplored. Existing research only separates an image into easy and hard regions and empirically observes the latter are associated with object boundaries. In this paper, we conduct a comprehensive analysis of hard pixel errors, categorizing them into three types: false responses, merging mistakes, and displacements. Our findings reveal a quantitative association between hard pixels and aliasing, which is distortion caused by the overlapping of frequency components in the Fourier domain during downsampling. To identify the frequencies responsible for aliasing, we propose using the equivalent sampling rate to calculate the Nyquist frequency, which marks the threshold for aliasing. Then, we introduce the aliasing score as a metric to quantify the extent of aliasing. While positively correlated with the proposed aliasing score, three types of hard pixels exhibit different patterns. Here, we propose two novel de-aliasing filter (DAF) and frequency mixing (FreqMix) modules to alleviate aliasing degradation by accurately removing or adjusting frequencies higher than the Nyquist frequency. The DAF precisely removes the frequencies responsible for aliasing before downsampling, while the FreqMix dynamically selects high-frequency components within the encoder block. Experimental results demonstrate consistent improvements in semantic segmentation and low-light instance segmentation tasks. The code is available at: https://github.com/Linwei-Chen/Seg-Aliasing.

  • 3 authors
·
Mar 13, 2024

HER-Seg: Holistically Efficient Segmentation for High-Resolution Medical Images

High-resolution segmentation is critical for precise disease diagnosis by extracting fine-grained morphological details. Existing hierarchical encoder-decoder frameworks have demonstrated remarkable adaptability across diverse medical segmentation tasks. While beneficial, they usually require the huge computation and memory cost when handling large-size segmentation, which limits their applications in foundation model building and real-world clinical scenarios. To address this limitation, we propose a holistically efficient framework for high-resolution medical image segmentation, called HER-Seg. Specifically, we first devise a computation-efficient image encoder (CE-Encoder) to model long-range dependencies with linear complexity while maintaining sufficient representations. In particular, we introduce the dual-gated linear attention (DLA) mechanism to perform cascaded token filtering, selectively retaining important tokens while ignoring irrelevant ones to enhance attention computation efficiency. Then, we introduce a memory-efficient mask decoder (ME-Decoder) to eliminate the demand for the hierarchical structure by leveraging cross-scale segmentation decoding. Extensive experiments reveal that HER-Seg outperforms state-of-the-arts in high-resolution medical 2D, 3D and video segmentation tasks. In particular, our HER-Seg requires only 0.59GB training GPU memory and 9.39G inference FLOPs per 1024times1024 image, demonstrating superior memory and computation efficiency. The code is available at https://github.com/xq141839/HER-Seg.

  • 9 authors
·
Apr 8

Enhancing Brain Tumor Segmentation Using Channel Attention and Transfer learning

Accurate and efficient segmentation of brain tumors is critical for diagnosis, treatment planning, and monitoring in clinical practice. In this study, we present an enhanced ResUNet architecture for automatic brain tumor segmentation, integrating an EfficientNetB0 encoder, a channel attention mechanism, and an Atrous Spatial Pyramid Pooling (ASPP) module. The EfficientNetB0 encoder leverages pre-trained features to improve feature extraction efficiency, while the channel attention mechanism enhances the model's focus on tumor-relevant features. ASPP enables multiscale contextual learning, crucial for handling tumors of varying sizes and shapes. The proposed model was evaluated on two benchmark datasets: TCGA LGG and BraTS 2020. Experimental results demonstrate that our method consistently outperforms the baseline ResUNet and its EfficientNet variant, achieving Dice coefficients of 0.903 and 0.851 and HD95 scores of 9.43 and 3.54 for whole tumor and tumor core regions on the BraTS 2020 dataset, respectively. compared with state-of-the-art methods, our approach shows competitive performance, particularly in whole tumor and tumor core segmentation. These results indicate that combining a powerful encoder with attention mechanisms and ASPP can significantly enhance brain tumor segmentation performance. The proposed approach holds promise for further optimization and application in other medical image segmentation tasks.

  • 4 authors
·
Jan 19

InterFormer: Real-time Interactive Image Segmentation

Interactive image segmentation enables annotators to efficiently perform pixel-level annotation for segmentation tasks. However, the existing interactive segmentation pipeline suffers from inefficient computations of interactive models because of the following two issues. First, annotators' later click is based on models' feedback of annotators' former click. This serial interaction is unable to utilize model's parallelism capabilities. Second, in each interaction step, the model handles the invariant image along with the sparse variable clicks, resulting in a process that's highly repetitive and redundant. For efficient computations, we propose a method named InterFormer that follows a new pipeline to address these issues. InterFormer extracts and preprocesses the computationally time-consuming part i.e. image processing from the existing process. Specifically, InterFormer employs a large vision transformer (ViT) on high-performance devices to preprocess images in parallel, and then uses a lightweight module called interactive multi-head self attention (I-MSA) for interactive segmentation. Furthermore, the I-MSA module's deployment on low-power devices extends the practical application of interactive segmentation. The I-MSA module utilizes the preprocessed features to efficiently response to the annotator inputs in real-time. The experiments on several datasets demonstrate the effectiveness of InterFormer, which outperforms previous interactive segmentation models in terms of computational efficiency and segmentation quality, achieve real-time high-quality interactive segmentation on CPU-only devices. The code is available at https://github.com/YouHuang67/InterFormer.

  • 7 authors
·
Apr 6, 2023 2

Liver Segmentation using Turbolift Learning for CT and Cone-beam C-arm Perfusion Imaging

Model-based reconstruction employing the time separation technique (TST) was found to improve dynamic perfusion imaging of the liver using C-arm cone-beam computed tomography (CBCT). To apply TST using prior knowledge extracted from CT perfusion data, the liver should be accurately segmented from the CT scans. Reconstructions of primary and model-based CBCT data need to be segmented for proper visualisation and interpretation of perfusion maps. This research proposes Turbolift learning, which trains a modified version of the multi-scale Attention UNet on different liver segmentation tasks serially, following the order of the trainings CT, CBCT, CBCT TST - making the previous trainings act as pre-training stages for the subsequent ones - addressing the problem of limited number of datasets for training. For the final task of liver segmentation from CBCT TST, the proposed method achieved an overall Dice scores of 0.874pm0.031 and 0.905pm0.007 in 6-fold and 4-fold cross-validation experiments, respectively - securing statistically significant improvements over the model, which was trained only for that task. Experiments revealed that Turbolift not only improves the overall performance of the model but also makes it robust against artefacts originating from the embolisation materials and truncation artefacts. Additionally, in-depth analyses confirmed the order of the segmentation tasks. This paper shows the potential of segmenting the liver from CT, CBCT, and CBCT TST, learning from the available limited training data, which can possibly be used in the future for the visualisation and evaluation of the perfusion maps for the treatment evaluation of liver diseases.

  • 12 authors
·
Jul 20, 2022

HiMTok: Learning Hierarchical Mask Tokens for Image Segmentation with Large Multimodal Model

The remarkable performance of large multimodal models (LMMs) has attracted significant interest from the image segmentation community. To align with the next-token-prediction paradigm, current LMM-driven segmentation methods either use object boundary points to represent masks or introduce special segmentation tokens, whose hidden states are decoded by a segmentation model requiring the original image as input. However, these approaches often suffer from inadequate mask representation and complex architectures, limiting the potential of LMMs. In this work, we propose the Hierarchical Mask Tokenizer (HiMTok), which represents segmentation masks with up to 32 tokens and eliminates the need for the original image during mask de-tokenization. HiMTok allows for compact and coarse-to-fine mask representations, aligning well with the LLM next-token-prediction paradigm and facilitating the direct acquisition of segmentation capabilities. We develop a 3-stage training recipe for progressive learning of segmentation and visual capabilities, featuring a hierarchical mask loss for effective coarse-to-fine learning. Additionally, we enable bidirectional information flow, allowing conversion between bounding boxes and mask tokens to fully leverage multi-task training potential. Extensive experiments demonstrate that our method achieves state-of-the-art performance across various segmentation tasks,while also enhancing visual grounding and maintaining overall visual understanding.

  • 5 authors
·
Mar 17

UNIP: Rethinking Pre-trained Attention Patterns for Infrared Semantic Segmentation

Pre-training techniques significantly enhance the performance of semantic segmentation tasks with limited training data. However, the efficacy under a large domain gap between pre-training (e.g. RGB) and fine-tuning (e.g. infrared) remains underexplored. In this study, we first benchmark the infrared semantic segmentation performance of various pre-training methods and reveal several phenomena distinct from the RGB domain. Next, our layerwise analysis of pre-trained attention maps uncovers that: (1) There are three typical attention patterns (local, hybrid, and global); (2) Pre-training tasks notably influence the pattern distribution across layers; (3) The hybrid pattern is crucial for semantic segmentation as it attends to both nearby and foreground elements; (4) The texture bias impedes model generalization in infrared tasks. Building on these insights, we propose UNIP, a UNified Infrared Pre-training framework, to enhance the pre-trained model performance. This framework uses the hybrid-attention distillation NMI-HAD as the pre-training target, a large-scale mixed dataset InfMix for pre-training, and a last-layer feature pyramid network LL-FPN for fine-tuning. Experimental results show that UNIP outperforms various pre-training methods by up to 13.5\% in average mIoU on three infrared segmentation tasks, evaluated using fine-tuning and linear probing metrics. UNIP-S achieves performance on par with MAE-L while requiring only 1/10 of the computational cost. Furthermore, UNIP significantly surpasses state-of-the-art (SOTA) infrared or RGB segmentation methods and demonstrates broad potential for application in other modalities, such as RGB and depth. Our code is available at https://github.com/casiatao/UNIP.

  • 6 authors
·
Feb 4

QTSeg: A Query Token-Based Dual-Mix Attention Framework with Multi-Level Feature Distribution for Medical Image Segmentation

Medical image segmentation plays a crucial role in assisting healthcare professionals with accurate diagnoses and enabling automated diagnostic processes. Traditional convolutional neural networks (CNNs) often struggle with capturing long-range dependencies, while transformer-based architectures, despite their effectiveness, come with increased computational complexity. Recent efforts have focused on combining CNNs and transformers to balance performance and efficiency, but existing approaches still face challenges in achieving high segmentation accuracy while maintaining low computational costs. Furthermore, many methods underutilize the CNN encoder's capability to capture local spatial information, concentrating primarily on mitigating long-range dependency issues. To address these limitations, we propose QTSeg, a novel architecture for medical image segmentation that effectively integrates local and global information. QTSeg features a dual-mix attention decoder designed to enhance segmentation performance through: (1) a cross-attention mechanism for improved feature alignment, (2) a spatial attention module to capture long-range dependencies, and (3) a channel attention block to learn inter-channel relationships. Additionally, we introduce a multi-level feature distribution module, which adaptively balances feature propagation between the encoder and decoder, further boosting performance. Extensive experiments on five publicly available datasets covering diverse segmentation tasks, including lesion, polyp, breast cancer, cell, and retinal vessel segmentation, demonstrate that QTSeg outperforms state-of-the-art methods across multiple evaluation metrics while maintaining lower computational costs. Our implementation can be found at: https://github.com/tpnam0901/QTSeg (v1.0.0)

  • 5 authors
·
Dec 22, 2024

Object-Focused Data Selection for Dense Prediction Tasks

Dense prediction tasks such as object detection and segmentation require high-quality labels at pixel level, which are costly to obtain. Recent advances in foundation models have enabled the generation of autolabels, which we find to be competitive but not yet sufficient to fully replace human annotations, especially for more complex datasets. Thus, we consider the challenge of selecting a representative subset of images for labeling from a large pool of unlabeled images under a constrained annotation budget. This task is further complicated by imbalanced class distributions, as rare classes are often underrepresented in selected subsets. We propose object-focused data selection (OFDS) which leverages object-level representations to ensure that the selected image subsets semantically cover the target classes, including rare ones. We validate OFDS on PASCAL VOC and Cityscapes for object detection and semantic segmentation tasks. Our experiments demonstrate that prior methods which employ image-level representations fail to consistently outperform random selection. In contrast, OFDS consistently achieves state-of-the-art performance with substantial improvements over all baselines in scenarios with imbalanced class distributions. Moreover, we demonstrate that pre-training with autolabels on the full datasets before fine-tuning on human-labeled subsets selected by OFDS further enhances the final performance.

  • 5 authors
·
Dec 13, 2024

IndraEye: Infrared Electro-Optical UAV-based Perception Dataset for Robust Downstream Tasks

Deep neural networks (DNNs) have shown exceptional performance when trained on well-illuminated images captured by Electro-Optical (EO) cameras, which provide rich texture details. However, in critical applications like aerial perception, it is essential for DNNs to maintain consistent reliability across all conditions, including low-light scenarios where EO cameras often struggle to capture sufficient detail. Additionally, UAV-based aerial object detection faces significant challenges due to scale variability from varying altitudes and slant angles, adding another layer of complexity. Existing methods typically address only illumination changes or style variations as domain shifts, but in aerial perception, correlation shifts also impact DNN performance. In this paper, we introduce the IndraEye dataset, a multi-sensor (EO-IR) dataset designed for various tasks. It includes 5,612 images with 145,666 instances, encompassing multiple viewing angles, altitudes, seven backgrounds, and different times of the day across the Indian subcontinent. The dataset opens up several research opportunities, such as multimodal learning, domain adaptation for object detection and segmentation, and exploration of sensor-specific strengths and weaknesses. IndraEye aims to advance the field by supporting the development of more robust and accurate aerial perception systems, particularly in challenging conditions. IndraEye dataset is benchmarked with object detection and semantic segmentation tasks. Dataset and source codes are available at https://bit.ly/indraeye.

  • 7 authors
·
Oct 28, 2024

OneRef: Unified One-tower Expression Grounding and Segmentation with Mask Referring Modeling

Constrained by the separate encoding of vision and language, existing grounding and referring segmentation works heavily rely on bulky Transformer-based fusion en-/decoders and a variety of early-stage interaction technologies. Simultaneously, the current mask visual language modeling (MVLM) fails to capture the nuanced referential relationship between image-text in referring tasks. In this paper, we propose OneRef, a minimalist referring framework built on the modality-shared one-tower transformer that unifies the visual and linguistic feature spaces. To modeling the referential relationship, we introduce a novel MVLM paradigm called Mask Referring Modeling (MRefM), which encompasses both referring-aware mask image modeling and referring-aware mask language modeling. Both modules not only reconstruct modality-related content but also cross-modal referring content. Within MRefM, we propose a referring-aware dynamic image masking strategy that is aware of the referred region rather than relying on fixed ratios or generic random masking schemes. By leveraging the unified visual language feature space and incorporating MRefM's ability to model the referential relations, our approach enables direct regression of the referring results without resorting to various complex techniques. Our method consistently surpasses existing approaches and achieves SoTA performance on both grounding and segmentation tasks, providing valuable insights for future research. Our code and models are available at https://github.com/linhuixiao/OneRef.

  • 5 authors
·
Oct 10, 2024

PULASki: Learning inter-rater variability using statistical distances to improve probabilistic segmentation

In the domain of medical imaging, many supervised learning based methods for segmentation face several challenges such as high variability in annotations from multiple experts, paucity of labelled data and class imbalanced datasets. These issues may result in segmentations that lack the requisite precision for clinical analysis and can be misleadingly overconfident without associated uncertainty quantification. We propose the PULASki for biomedical image segmentation that accurately captures variability in expert annotations, even in small datasets. Our approach makes use of an improved loss function based on statistical distances in a conditional variational autoencoder structure (Probabilistic UNet), which improves learning of the conditional decoder compared to the standard cross-entropy particularly in class imbalanced problems. We analyse our method for two structurally different segmentation tasks (intracranial vessel and multiple sclerosis (MS) lesion) and compare our results to four well-established baselines in terms of quantitative metrics and qualitative output. Empirical results demonstrate the PULASKi method outperforms all baselines at the 5\% significance level. The generated segmentations are shown to be much more anatomically plausible than in the 2D case, particularly for the vessel task. Our method can also be applied to a wide range of multi-label segmentation tasks and and is useful for downstream tasks such as hemodynamic modelling (computational fluid dynamics and data assimilation), clinical decision making, and treatment planning.

  • 8 authors
·
Dec 25, 2023

SEGIC: Unleashing the Emergent Correspondence for In-Context Segmentation

In-context segmentation aims at segmenting novel images using a few labeled example images, termed as "in-context examples", exploring content similarities between examples and the target. The resulting models can be generalized seamlessly to novel segmentation tasks, significantly reducing the labeling and training costs compared with conventional pipelines. However, in-context segmentation is more challenging than classic ones due to its meta-learning nature, requiring the model to learn segmentation rules conditioned on a few samples, not just the segmentation. Unlike previous work with ad-hoc or non-end-to-end designs, we propose SEGIC, an end-to-end segment-in-context framework built upon a single vision foundation model (VFM). In particular, SEGIC leverages the emergent correspondence within VFM to capture dense relationships between target images and in-context samples. As such, information from in-context samples is then extracted into three types of instructions, i.e. geometric, visual, and meta instructions, serving as explicit conditions for the final mask prediction. SEGIC is a straightforward yet effective approach that yields state-of-the-art performance on one-shot segmentation benchmarks. Notably, SEGIC can be easily generalized to diverse tasks, including video object segmentation and open-vocabulary segmentation. Code will be available at https://github.com/MengLcool/SEGIC.

  • 6 authors
·
Nov 24, 2023

Devil is in the Queries: Advancing Mask Transformers for Real-world Medical Image Segmentation and Out-of-Distribution Localization

Real-world medical image segmentation has tremendous long-tailed complexity of objects, among which tail conditions correlate with relatively rare diseases and are clinically significant. A trustworthy medical AI algorithm should demonstrate its effectiveness on tail conditions to avoid clinically dangerous damage in these out-of-distribution (OOD) cases. In this paper, we adopt the concept of object queries in Mask Transformers to formulate semantic segmentation as a soft cluster assignment. The queries fit the feature-level cluster centers of inliers during training. Therefore, when performing inference on a medical image in real-world scenarios, the similarity between pixels and the queries detects and localizes OOD regions. We term this OOD localization as MaxQuery. Furthermore, the foregrounds of real-world medical images, whether OOD objects or inliers, are lesions. The difference between them is less than that between the foreground and background, possibly misleading the object queries to focus redundantly on the background. Thus, we propose a query-distribution (QD) loss to enforce clear boundaries between segmentation targets and other regions at the query level, improving the inlier segmentation and OOD indication. Our proposed framework is tested on two real-world segmentation tasks, i.e., segmentation of pancreatic and liver tumors, outperforming previous state-of-the-art algorithms by an average of 7.39% on AUROC, 14.69% on AUPR, and 13.79% on FPR95 for OOD localization. On the other hand, our framework improves the performance of inlier segmentation by an average of 5.27% DSC when compared with the leading baseline nnUNet.

  • 16 authors
·
Mar 31, 2023

Weakly-supervised segmentation using inherently-explainable classification models and their application to brain tumour classification

Deep learning models have shown their potential for several applications. However, most of the models are opaque and difficult to trust due to their complex reasoning - commonly known as the black-box problem. Some fields, such as medicine, require a high degree of transparency to accept and adopt such technologies. Consequently, creating explainable/interpretable models or applying post-hoc methods on classifiers to build trust in deep learning models are required. Moreover, deep learning methods can be used for segmentation tasks, which typically require hard-to-obtain, time-consuming manually-annotated segmentation labels for training. This paper introduces three inherently-explainable classifiers to tackle both of these problems as one. The localisation heatmaps provided by the networks -- representing the models' focus areas and being used in classification decision-making -- can be directly interpreted, without requiring any post-hoc methods to derive information for model explanation. The models are trained by using the input image and only the classification labels as ground-truth in a supervised fashion - without using any information about the location of the region of interest (i.e. the segmentation labels), making the segmentation training of the models weakly-supervised through classification labels. The final segmentation is obtained by thresholding these heatmaps. The models were employed for the task of multi-class brain tumour classification using two different datasets, resulting in the best F1-score of 0.93 for the supervised classification task while securing a median Dice score of 0.67pm0.08 for the weakly-supervised segmentation task. Furthermore, the obtained accuracy on a subset of tumour-only images outperformed the state-of-the-art glioma tumour grading binary classifiers with the best model achieving 98.7\% accuracy.

  • 5 authors
·
Jun 10, 2022

The Liver Tumor Segmentation Benchmark (LiTS)

In this work, we report the set-up and results of the Liver Tumor Segmentation Benchmark (LiTS), which was organized in conjunction with the IEEE International Symposium on Biomedical Imaging (ISBI) 2017 and the International Conferences on Medical Image Computing and Computer-Assisted Intervention (MICCAI) 2017 and 2018. The image dataset is diverse and contains primary and secondary tumors with varied sizes and appearances with various lesion-to-background levels (hyper-/hypo-dense), created in collaboration with seven hospitals and research institutions. Seventy-five submitted liver and liver tumor segmentation algorithms were trained on a set of 131 computed tomography (CT) volumes and were tested on 70 unseen test images acquired from different patients. We found that not a single algorithm performed best for both liver and liver tumors in the three events. The best liver segmentation algorithm achieved a Dice score of 0.963, whereas, for tumor segmentation, the best algorithms achieved Dices scores of 0.674 (ISBI 2017), 0.702 (MICCAI 2017), and 0.739 (MICCAI 2018). Retrospectively, we performed additional analysis on liver tumor detection and revealed that not all top-performing segmentation algorithms worked well for tumor detection. The best liver tumor detection method achieved a lesion-wise recall of 0.458 (ISBI 2017), 0.515 (MICCAI 2017), and 0.554 (MICCAI 2018), indicating the need for further research. LiTS remains an active benchmark and resource for research, e.g., contributing the liver-related segmentation tasks in http://medicaldecathlon.com/. In addition, both data and online evaluation are accessible via www.lits-challenge.com.

  • 109 authors
·
Jan 13, 2019

COCONut: Modernizing COCO Segmentation

In recent decades, the vision community has witnessed remarkable progress in visual recognition, partially owing to advancements in dataset benchmarks. Notably, the established COCO benchmark has propelled the development of modern detection and segmentation systems. However, the COCO segmentation benchmark has seen comparatively slow improvement over the last decade. Originally equipped with coarse polygon annotations for thing instances, it gradually incorporated coarse superpixel annotations for stuff regions, which were subsequently heuristically amalgamated to yield panoptic segmentation annotations. These annotations, executed by different groups of raters, have resulted not only in coarse segmentation masks but also in inconsistencies between segmentation types. In this study, we undertake a comprehensive reevaluation of the COCO segmentation annotations. By enhancing the annotation quality and expanding the dataset to encompass 383K images with more than 5.18M panoptic masks, we introduce COCONut, the COCO Next Universal segmenTation dataset. COCONut harmonizes segmentation annotations across semantic, instance, and panoptic segmentation with meticulously crafted high-quality masks, and establishes a robust benchmark for all segmentation tasks. To our knowledge, COCONut stands as the inaugural large-scale universal segmentation dataset, verified by human raters. We anticipate that the release of COCONut will significantly contribute to the community's ability to assess the progress of novel neural networks.

  • 5 authors
·
Apr 12, 2024 6

UniPixel: Unified Object Referring and Segmentation for Pixel-Level Visual Reasoning

Recent advances in Large Multi-modal Models (LMMs) have demonstrated their remarkable success as general-purpose multi-modal assistants, with particular focuses on holistic image- and video-language understanding. Conversely, less attention has been given to scaling fine-grained pixel-level understanding capabilities, where the models are expected to realize pixel-level alignment between visual signals and language semantics. Some previous studies have applied LMMs to related tasks such as region-level captioning and referring expression segmentation. However, these models are limited to performing either referring or segmentation tasks independently and fail to integrate these fine-grained perception capabilities into visual reasoning. To bridge this gap, we propose UniPixel, a large multi-modal model capable of flexibly comprehending visual prompt inputs and generating mask-grounded responses. Our model distinguishes itself by seamlessly integrating pixel-level perception with general visual understanding capabilities. Specifically, UniPixel processes visual prompts and generates relevant masks on demand, and performs subsequent reasoning conditioning on these intermediate pointers during inference, thereby enabling fine-grained pixel-level reasoning. The effectiveness of our approach has been verified on 10 benchmarks across a diverse set of tasks, including pixel-level referring/segmentation and object-centric understanding in images/videos. A novel PixelQA task that jointly requires referring, segmentation, and question answering is also designed to verify the flexibility of our method.

  • 7 authors
·
Sep 22 3

Swin UNETR: Swin Transformers for Semantic Segmentation of Brain Tumors in MRI Images

Semantic segmentation of brain tumors is a fundamental medical image analysis task involving multiple MRI imaging modalities that can assist clinicians in diagnosing the patient and successively studying the progression of the malignant entity. In recent years, Fully Convolutional Neural Networks (FCNNs) approaches have become the de facto standard for 3D medical image segmentation. The popular "U-shaped" network architecture has achieved state-of-the-art performance benchmarks on different 2D and 3D semantic segmentation tasks and across various imaging modalities. However, due to the limited kernel size of convolution layers in FCNNs, their performance of modeling long-range information is sub-optimal, and this can lead to deficiencies in the segmentation of tumors with variable sizes. On the other hand, transformer models have demonstrated excellent capabilities in capturing such long-range information in multiple domains, including natural language processing and computer vision. Inspired by the success of vision transformers and their variants, we propose a novel segmentation model termed Swin UNEt TRansformers (Swin UNETR). Specifically, the task of 3D brain tumor semantic segmentation is reformulated as a sequence to sequence prediction problem wherein multi-modal input data is projected into a 1D sequence of embedding and used as an input to a hierarchical Swin transformer as the encoder. The swin transformer encoder extracts features at five different resolutions by utilizing shifted windows for computing self-attention and is connected to an FCNN-based decoder at each resolution via skip connections. We have participated in BraTS 2021 segmentation challenge, and our proposed model ranks among the top-performing approaches in the validation phase. Code: https://monai.io/research/swin-unetr

  • 6 authors
·
Jan 4, 2022

VISA: Reasoning Video Object Segmentation via Large Language Models

Existing Video Object Segmentation (VOS) relies on explicit user instructions, such as categories, masks, or short phrases, restricting their ability to perform complex video segmentation requiring reasoning with world knowledge. In this paper, we introduce a new task, Reasoning Video Object Segmentation (ReasonVOS). This task aims to generate a sequence of segmentation masks in response to implicit text queries that require complex reasoning abilities based on world knowledge and video contexts, which is crucial for structured environment understanding and object-centric interactions, pivotal in the development of embodied AI. To tackle ReasonVOS, we introduce VISA (Video-based large language Instructed Segmentation Assistant), to leverage the world knowledge reasoning capabilities of multi-modal LLMs while possessing the ability to segment and track objects in videos with a mask decoder. Moreover, we establish a comprehensive benchmark consisting of 35,074 instruction-mask sequence pairs from 1,042 diverse videos, which incorporates complex world knowledge reasoning into segmentation tasks for instruction-tuning and evaluation purposes of ReasonVOS models. Experiments conducted on 8 datasets demonstrate the effectiveness of VISA in tackling complex reasoning segmentation and vanilla referring segmentation in both video and image domains. The code and dataset are available at https://github.com/cilinyan/VISA.

  • 8 authors
·
Jul 15, 2024

PEM: Prototype-based Efficient MaskFormer for Image Segmentation

Recent transformer-based architectures have shown impressive results in the field of image segmentation. Thanks to their flexibility, they obtain outstanding performance in multiple segmentation tasks, such as semantic and panoptic, under a single unified framework. To achieve such impressive performance, these architectures employ intensive operations and require substantial computational resources, which are often not available, especially on edge devices. To fill this gap, we propose Prototype-based Efficient MaskFormer (PEM), an efficient transformer-based architecture that can operate in multiple segmentation tasks. PEM proposes a novel prototype-based cross-attention which leverages the redundancy of visual features to restrict the computation and improve the efficiency without harming the performance. In addition, PEM introduces an efficient multi-scale feature pyramid network, capable of extracting features that have high semantic content in an efficient way, thanks to the combination of deformable convolutions and context-based self-modulation. We benchmark the proposed PEM architecture on two tasks, semantic and panoptic segmentation, evaluated on two different datasets, Cityscapes and ADE20K. PEM demonstrates outstanding performance on every task and dataset, outperforming task-specific architectures while being comparable and even better than computationally-expensive baselines.

  • 7 authors
·
Feb 29, 2024

DGInStyle: Domain-Generalizable Semantic Segmentation with Image Diffusion Models and Stylized Semantic Control

Large, pretrained latent diffusion models (LDMs) have demonstrated an extraordinary ability to generate creative content, specialize to user data through few-shot fine-tuning, and condition their output on other modalities, such as semantic maps. However, are they usable as large-scale data generators, e.g., to improve tasks in the perception stack, like semantic segmentation? We investigate this question in the context of autonomous driving, and answer it with a resounding "yes". We propose an efficient data generation pipeline termed DGInStyle. First, we examine the problem of specializing a pretrained LDM to semantically-controlled generation within a narrow domain. Second, we design a Multi-resolution Latent Fusion technique to overcome the bias of LDMs towards dominant objects. Third, we propose a Style Swap technique to endow the rich generative prior with the learned semantic control. Using DGInStyle, we generate a diverse dataset of street scenes, train a domain-agnostic semantic segmentation model on it, and evaluate the model on multiple popular autonomous driving datasets. Our approach consistently increases the performance of several domain generalization methods, in some cases by +2.5 mIoU compared to the previous state-of-the-art method without our generative augmentation scheme. Source code and dataset are available at https://dginstyle.github.io .

LISA: Reasoning Segmentation via Large Language Model

Although perception systems have made remarkable advancements in recent years, they still rely on explicit human instruction to identify the target objects or categories before executing visual recognition tasks. Such systems lack the ability to actively reason and comprehend implicit user intentions. In this work, we propose a new segmentation task -- reasoning segmentation. The task is designed to output a segmentation mask given a complex and implicit query text. Furthermore, we establish a benchmark comprising over one thousand image-instruction pairs, incorporating intricate reasoning and world knowledge for evaluation purposes. Finally, we present LISA: large Language Instructed Segmentation Assistant, which inherits the language generation capabilities of the multi-modal Large Language Model (LLM) while also possessing the ability to produce segmentation masks. We expand the original vocabulary with a <SEG> token and propose the embedding-as-mask paradigm to unlock the segmentation capability. Remarkably, LISA can handle cases involving: 1) complex reasoning; 2) world knowledge; 3) explanatory answers; 4) multi-turn conversation. Also, it demonstrates robust zero-shot capability when trained exclusively on reasoning-free datasets. In addition, fine-tuning the model with merely 239 reasoning segmentation image-instruction pairs results in further performance enhancement. Experiments show our method not only unlocks new reasoning segmentation capabilities but also proves effective in both complex reasoning segmentation and standard referring segmentation tasks. Code, models, and demo are at https://github.com/dvlab-research/LISA.

  • 7 authors
·
Aug 1, 2023 1

CADS: A Comprehensive Anatomical Dataset and Segmentation for Whole-Body Anatomy in Computed Tomography

Accurate delineation of anatomical structures in volumetric CT scans is crucial for diagnosis and treatment planning. While AI has advanced automated segmentation, current approaches typically target individual structures, creating a fragmented landscape of incompatible models with varying performance and disparate evaluation protocols. Foundational segmentation models address these limitations by providing a holistic anatomical view through a single model. Yet, robust clinical deployment demands comprehensive training data, which is lacking in existing whole-body approaches, both in terms of data heterogeneity and, more importantly, anatomical coverage. In this work, rather than pursuing incremental optimizations in model architecture, we present CADS, an open-source framework that prioritizes the systematic integration, standardization, and labeling of heterogeneous data sources for whole-body CT segmentation. At its core is a large-scale dataset of 22,022 CT volumes with complete annotations for 167 anatomical structures, representing a significant advancement in both scale and coverage, with 18 times more scans than existing collections and 60% more distinct anatomical targets. Building on this diverse dataset, we develop the CADS-model using established architectures for accessible and automated full-body CT segmentation. Through comprehensive evaluation across 18 public datasets and an independent real-world hospital cohort, we demonstrate advantages over SoTA approaches. Notably, thorough testing of the model's performance in segmentation tasks from radiation oncology validates its direct utility for clinical interventions. By making our large-scale dataset, our segmentation models, and our clinical software tool publicly available, we aim to advance robust AI solutions in radiology and make comprehensive anatomical analysis accessible to clinicians and researchers alike.

  • 33 authors
·
Jul 29

LSMS: Language-guided Scale-aware MedSegmentor for Medical Image Referring Segmentation

Conventional medical image segmentation methods have been found inadequate in facilitating physicians with the identification of specific lesions for diagnosis and treatment. Given the utility of text as an instructional format, we introduce a novel task termed Medical Image Referring Segmentation (MIRS), which requires segmenting specified lesions in images based on the given language expressions. Due to the varying object scales in medical images, MIRS demands robust vision-language modeling and comprehensive multi-scale interaction for precise localization and segmentation under linguistic guidance. However, existing medical image segmentation methods fall short in meeting these demands, resulting in insufficient segmentation accuracy. In response, we propose an approach named Language-guided Scale-aware MedSegmentor (LSMS), incorporating two appealing designs: (1)~a Scale-aware Vision-Language Attention module that leverages diverse convolutional kernels to acquire rich visual knowledge and interact closely with linguistic features, thereby enhancing lesion localization capability; (2)~a Full-Scale Decoder that globally models multi-modal features across various scales, capturing complementary information between scales to accurately outline lesion boundaries. Addressing the lack of suitable datasets for MIRS, we constructed a vision-language medical dataset called Reference Hepatic Lesion Segmentation (RefHL-Seg). This dataset comprises 2,283 abdominal CT slices from 231 cases, with corresponding textual annotations and segmentation masks for various liver lesions in images. We validated the performance of LSMS for MIRS and conventional medical image segmentation tasks across various datasets. Our LSMS consistently outperforms on all datasets with lower computational costs. The code and datasets will be released.

  • 7 authors
·
Aug 30, 2024

OneFormer: One Transformer to Rule Universal Image Segmentation

Universal Image Segmentation is not a new concept. Past attempts to unify image segmentation in the last decades include scene parsing, panoptic segmentation, and, more recently, new panoptic architectures. However, such panoptic architectures do not truly unify image segmentation because they need to be trained individually on the semantic, instance, or panoptic segmentation to achieve the best performance. Ideally, a truly universal framework should be trained only once and achieve SOTA performance across all three image segmentation tasks. To that end, we propose OneFormer, a universal image segmentation framework that unifies segmentation with a multi-task train-once design. We first propose a task-conditioned joint training strategy that enables training on ground truths of each domain (semantic, instance, and panoptic segmentation) within a single multi-task training process. Secondly, we introduce a task token to condition our model on the task at hand, making our model task-dynamic to support multi-task training and inference. Thirdly, we propose using a query-text contrastive loss during training to establish better inter-task and inter-class distinctions. Notably, our single OneFormer model outperforms specialized Mask2Former models across all three segmentation tasks on ADE20k, CityScapes, and COCO, despite the latter being trained on each of the three tasks individually with three times the resources. With new ConvNeXt and DiNAT backbones, we observe even more performance improvement. We believe OneFormer is a significant step towards making image segmentation more universal and accessible. To support further research, we open-source our code and models at https://github.com/SHI-Labs/OneFormer

  • 6 authors
·
Nov 10, 2022

Annotation-Efficient Learning for Medical Image Segmentation based on Noisy Pseudo Labels and Adversarial Learning

Despite that deep learning has achieved state-of-the-art performance for medical image segmentation, its success relies on a large set of manually annotated images for training that are expensive to acquire. In this paper, we propose an annotation-efficient learning framework for segmentation tasks that avoids annotations of training images, where we use an improved Cycle-Consistent Generative Adversarial Network (GAN) to learn from a set of unpaired medical images and auxiliary masks obtained either from a shape model or public datasets. We first use the GAN to generate pseudo labels for our training images under the implicit high-level shape constraint represented by a Variational Auto-encoder (VAE)-based discriminator with the help of the auxiliary masks, and build a Discriminator-guided Generator Channel Calibration (DGCC) module which employs our discriminator's feedback to calibrate the generator for better pseudo labels. To learn from the pseudo labels that are noisy, we further introduce a noise-robust iterative learning method using noise-weighted Dice loss. We validated our framework with two situations: objects with a simple shape model like optic disc in fundus images and fetal head in ultrasound images, and complex structures like lung in X-Ray images and liver in CT images. Experimental results demonstrated that 1) Our VAE-based discriminator and DGCC module help to obtain high-quality pseudo labels. 2) Our proposed noise-robust learning method can effectively overcome the effect of noisy pseudo labels. 3) The segmentation performance of our method without using annotations of training images is close or even comparable to that of learning from human annotations.

  • 4 authors
·
Dec 28, 2020

Leveraging Out-of-Distribution Unlabeled Images: Semi-Supervised Semantic Segmentation with an Open-Vocabulary Model

In semi-supervised semantic segmentation, existing studies have shown promising results in academic settings with controlled splits of benchmark datasets. However, the potential benefits of leveraging significantly larger sets of unlabeled images remain unexplored. In real-world scenarios, abundant unlabeled images are often available from online sources (web-scraped images) or large-scale datasets. However, these images may have different distributions from those of the target dataset, a situation known as out-of-distribution (OOD). Using these images as unlabeled data in semi-supervised learning can lead to inaccurate pseudo-labels, potentially misguiding network training. In this paper, we propose a new semi-supervised semantic segmentation framework with an open-vocabulary segmentation model (SemiOVS) to effectively utilize unlabeled OOD images. Extensive experiments on Pascal VOC and Context datasets demonstrate two key findings: (1) using additional unlabeled images improves the performance of semi-supervised learners in scenarios with few labels, and (2) using the open-vocabulary segmentation (OVS) model to pseudo-label OOD images leads to substantial performance gains. In particular, SemiOVS outperforms existing PrevMatch and SemiVL methods by +3.5 and +3.0 mIoU, respectively, on Pascal VOC with a 92-label setting, achieving state-of-the-art performance. These findings demonstrate that our approach effectively utilizes abundant unlabeled OOD images for semantic segmentation tasks. We hope this work can inspire future research and real-world applications. The code is available at https://github.com/wooseok-shin/SemiOVS

  • 5 authors
·
Jul 4

The revenge of BiSeNet: Efficient Multi-Task Image Segmentation

Recent advancements in image segmentation have focused on enhancing the efficiency of the models to meet the demands of real-time applications, especially on edge devices. However, existing research has primarily concentrated on single-task settings, especially on semantic segmentation, leading to redundant efforts and specialized architectures for different tasks. To address this limitation, we propose a novel architecture for efficient multi-task image segmentation, capable of handling various segmentation tasks without sacrificing efficiency or accuracy. We introduce BiSeNetFormer, that leverages the efficiency of two-stream semantic segmentation architectures and it extends them into a mask classification framework. Our approach maintains the efficient spatial and context paths to capture detailed and semantic information, respectively, while leveraging an efficient transformed-based segmentation head that computes the binary masks and class probabilities. By seamlessly supporting multiple tasks, namely semantic and panoptic segmentation, BiSeNetFormer offers a versatile solution for multi-task segmentation. We evaluate our approach on popular datasets, Cityscapes and ADE20K, demonstrating impressive inference speeds while maintaining competitive accuracy compared to state-of-the-art architectures. Our results indicate that BiSeNetFormer represents a significant advancement towards fast, efficient, and multi-task segmentation networks, bridging the gap between model efficiency and task adaptability.

  • 5 authors
·
Apr 15, 2024

RSVP: Reasoning Segmentation via Visual Prompting and Multi-modal Chain-of-Thought

Multi-modal Large Language Models (MLLMs) have demonstrated remarkable reasoning capability while lack explicit mechanisms for visual grounding and segmentation, creating a gap between cognitive reasoning and visual perception. To bridge this gap, we introduce Reasoning Segmentation via Visual Prompting (RSVP), a novel framework that unifies multi-step multimodal reasoning with grounded visual understanding. RSVP is a two-stage structuralized framework that integrates reasoning-driven localization with segmentation refinement. In the reasoning stage, RSVP employs multimodal chain-of-thought visual prompts to help MLLMs understand queries and infer targets, generating interpretable region proposals that enhance visual grounding. In segmentation stage, RSVP refines these proposals with a Vision-Language Segmentation Module (VLSM), seamlessly integrates textual and visual cues to produce precise segmentation masks. By explicitly modelling the interaction between multimodal reasoning and segmentation, RSVP introduces a new paradigm for interpretable reasoning segmentation. It exploits MLLMs' inherent localization capabilities, enabling the models to not only reason about objects but also generate structured visual representations. Our extensive experiments demonstrate that RSVP achieves state-of-the-art performance, surpasses state-of-the-art methods by up to +6.5 gIoU and +9.2 cIoU on ReasonSeg, and achieves 49.7 mAP on SegInW under zero-shot settings. These results validate RSVP as an effective and scalable framework for integrating cognitive reasoning with structured visual understanding.

  • 9 authors
·
Jun 3

OmniSAM: Omnidirectional Segment Anything Model for UDA in Panoramic Semantic Segmentation

Segment Anything Model 2 (SAM2) has emerged as a strong base model in various pinhole imaging segmentation tasks. However, when applying it to 360^circ domain, the significant field-of-view (FoV) gap between pinhole (70^circ times 70^circ) and panoramic images (180^circ times 360^circ) poses unique challenges. Two major concerns for this application includes 1) inevitable distortion and object deformation brought by the large FoV disparity between domains; 2) the lack of pixel-level semantic understanding that the original SAM2 cannot provide. To address these issues, we propose a novel OmniSAM framework, which makes the first attempt to apply SAM2 for panoramic semantic segmentation. Specifically, to bridge the first gap, OmniSAM first divides the panorama into sequences of patches. These patches are then treated as image sequences in similar manners as in video segmentation tasks. We then leverage the SAM2's memory mechanism to extract cross-patch correspondences that embeds the cross-FoV dependencies, improving feature continuity and the prediction consistency along mask boundaries. For the second gap, OmniSAM fine-tunes the pretrained image encoder and reutilize the mask decoder for semantic prediction. An FoV-based prototypical adaptation module with dynamic pseudo label update mechanism is also introduced to facilitate the alignment of memory and backbone features, thereby improving model generalization ability across different sizes of source models. Extensive experimental results demonstrate that OmniSAM outperforms the state-of-the-art methods by large margins, e.g., 79.06% (+10.22%) on SPin8-to-SPan8, 62.46% (+6.58%) on CS13-to-DP13.

  • 8 authors
·
Mar 10

SAM-UNet:Enhancing Zero-Shot Segmentation of SAM for Universal Medical Images

Segment Anything Model (SAM) has demonstrated impressive performance on a wide range of natural image segmentation tasks. However, its performance significantly deteriorates when directly applied to medical domain, due to the remarkable differences between natural images and medical images. Some researchers have attempted to train SAM on large scale medical datasets. However, poor zero-shot performance is observed from the experimental results. In this context, inspired by the superior performance of U-Net-like models in medical image segmentation, we propose SAMUNet, a new foundation model which incorporates U-Net to the original SAM, to fully leverage the powerful contextual modeling ability of convolutions. To be specific, we parallel a convolutional branch in the image encoder, which is trained independently with the vision Transformer branch frozen. Additionally, we employ multi-scale fusion in the mask decoder, to facilitate accurate segmentation of objects with different scales. We train SAM-UNet on SA-Med2D-16M, the largest 2-dimensional medical image segmentation dataset to date, yielding a universal pretrained model for medical images. Extensive experiments are conducted to evaluate the performance of the model, and state-of-the-art result is achieved, with a dice similarity coefficient score of 0.883 on SA-Med2D-16M dataset. Specifically, in zero-shot segmentation experiments, our model not only significantly outperforms previous large medical SAM models across all modalities, but also substantially mitigates the performance degradation seen on unseen modalities. It should be highlighted that SAM-UNet is an efficient and extensible foundation model, which can be further fine-tuned for other downstream tasks in medical community. The code is available at https://github.com/Hhankyangg/sam-unet.

  • 4 authors
·
Aug 19, 2024

Topologically faithful image segmentation via induced matching of persistence barcodes

Image segmentation is a largely researched field where neural networks find vast applications in many facets of technology. Some of the most popular approaches to train segmentation networks employ loss functions optimizing pixel-overlap, an objective that is insufficient for many segmentation tasks. In recent years, their limitations fueled a growing interest in topology-aware methods, which aim to recover the correct topology of the segmented structures. However, so far, none of the existing approaches achieve a spatially correct matching between the topological features of ground truth and prediction. In this work, we propose the first topologically and feature-wise accurate metric and loss function for supervised image segmentation, which we term Betti matching. We show how induced matchings guarantee the spatially correct matching between barcodes in a segmentation setting. Furthermore, we propose an efficient algorithm to compute the Betti matching of images. We show that the Betti matching error is an interpretable metric to evaluate the topological correctness of segmentations, which is more sensitive than the well-established Betti number error. Moreover, the differentiability of the Betti matching loss enables its use as a loss function. It improves the topological performance of segmentation networks across six diverse datasets while preserving the volumetric performance. Our code is available in https://github.com/nstucki/Betti-matching.

  • 5 authors
·
Nov 28, 2022

SegBook: A Simple Baseline and Cookbook for Volumetric Medical Image Segmentation

Computed Tomography (CT) is one of the most popular modalities for medical imaging. By far, CT images have contributed to the largest publicly available datasets for volumetric medical segmentation tasks, covering full-body anatomical structures. Large amounts of full-body CT images provide the opportunity to pre-train powerful models, e.g., STU-Net pre-trained in a supervised fashion, to segment numerous anatomical structures. However, it remains unclear in which conditions these pre-trained models can be transferred to various downstream medical segmentation tasks, particularly segmenting the other modalities and diverse targets. To address this problem, a large-scale benchmark for comprehensive evaluation is crucial for finding these conditions. Thus, we collected 87 public datasets varying in modality, target, and sample size to evaluate the transfer ability of full-body CT pre-trained models. We then employed a representative model, STU-Net with multiple model scales, to conduct transfer learning across modalities and targets. Our experimental results show that (1) there may be a bottleneck effect concerning the dataset size in fine-tuning, with more improvement on both small- and large-scale datasets than medium-size ones. (2) Models pre-trained on full-body CT demonstrate effective modality transfer, adapting well to other modalities such as MRI. (3) Pre-training on the full-body CT not only supports strong performance in structure detection but also shows efficacy in lesion detection, showcasing adaptability across target tasks. We hope that this large-scale open evaluation of transfer learning can direct future research in volumetric medical image segmentation.

  • 10 authors
·
Nov 21, 2024 2

Few-Shot Anomaly-Driven Generation for Anomaly Classification and Segmentation

Anomaly detection is a practical and challenging task due to the scarcity of anomaly samples in industrial inspection. Some existing anomaly detection methods address this issue by synthesizing anomalies with noise or external data. However, there is always a large semantic gap between synthetic and real-world anomalies, resulting in weak performance in anomaly detection. To solve the problem, we propose a few-shot Anomaly-driven Generation (AnoGen) method, which guides the diffusion model to generate realistic and diverse anomalies with only a few real anomalies, thereby benefiting training anomaly detection models. Specifically, our work is divided into three stages. In the first stage, we learn the anomaly distribution based on a few given real anomalies and inject the learned knowledge into an embedding. In the second stage, we use the embedding and given bounding boxes to guide the diffusion model to generate realistic and diverse anomalies on specific objects (or textures). In the final stage, we propose a weakly-supervised anomaly detection method to train a more powerful model with generated anomalies. Our method builds upon DRAEM and DesTSeg as the foundation model and conducts experiments on the commonly used industrial anomaly detection dataset, MVTec. The experiments demonstrate that our generated anomalies effectively improve the model performance of both anomaly classification and segmentation tasks simultaneously, \eg, DRAEM and DseTSeg achieved a 5.8\% and 1.5\% improvement in AU-PR metric on segmentation task, respectively. The code and generated anomalous data are available at https://github.com/gaobb/AnoGen.

  • 5 authors
·
May 14 2

Unveiling the Potential of Segment Anything Model 2 for RGB-Thermal Semantic Segmentation with Language Guidance

The perception capability of robotic systems relies on the richness of the dataset. Although Segment Anything Model 2 (SAM2), trained on large datasets, demonstrates strong perception potential in perception tasks, its inherent training paradigm prevents it from being suitable for RGB-T tasks. To address these challenges, we propose SHIFNet, a novel SAM2-driven Hybrid Interaction Paradigm that unlocks the potential of SAM2 with linguistic guidance for efficient RGB-Thermal perception. Our framework consists of two key components: (1) Semantic-Aware Cross-modal Fusion (SACF) module that dynamically balances modality contributions through text-guided affinity learning, overcoming SAM2's inherent RGB bias; (2) Heterogeneous Prompting Decoder (HPD) that enhances global semantic information through a semantic enhancement module and then combined with category embeddings to amplify cross-modal semantic consistency. With 32.27M trainable parameters, SHIFNet achieves state-of-the-art segmentation performance on public benchmarks, reaching 89.8% on PST900 and 67.8% on FMB, respectively. The framework facilitates the adaptation of pre-trained large models to RGB-T segmentation tasks, effectively mitigating the high costs associated with data collection while endowing robotic systems with comprehensive perception capabilities. The source code will be made publicly available at https://github.com/iAsakiT3T/SHIFNet.

  • 7 authors
·
Mar 4

SegNet4D: Efficient Instance-Aware 4D Semantic Segmentation for LiDAR Point Cloud

4D LiDAR semantic segmentation, also referred to as multi-scan semantic segmentation, plays a crucial role in enhancing the environmental understanding capabilities of autonomous vehicles or robots. It classifies the semantic category of each LiDAR measurement point and detects whether it is dynamic, a critical ability for tasks like obstacle avoidance and autonomous navigation. Existing approaches often rely on computationally heavy 4D convolutions or recursive networks, which result in poor real-time performance, making them unsuitable for online robotics and autonomous driving applications. In this paper, we introduce SegNet4D, a novel real-time 4D semantic segmentation network offering both efficiency and strong semantic understanding. SegNet4D addresses 4D segmentation as two tasks: single-scan semantic segmentation and moving object segmentation, each tackled by a separate network head. Both results are combined in a motion-semantic fusion module to achieve comprehensive 4D segmentation. Additionally, instance information is extracted from the current scan and exploited for instance-wise segmentation consistency. Our approach surpasses state-of-the-art in both multi-scan semantic segmentation and moving object segmentation while offering greater efficiency, enabling real-time operation. Besides, its effectiveness and efficiency have also been validated on a real-world unmanned ground platform. Our code will be released at https://github.com/nubot-nudt/SegNet4D.

  • 8 authors
·
Jun 23, 2024

LAC: Latent Action Composition for Skeleton-based Action Segmentation

Skeleton-based action segmentation requires recognizing composable actions in untrimmed videos. Current approaches decouple this problem by first extracting local visual features from skeleton sequences and then processing them by a temporal model to classify frame-wise actions. However, their performances remain limited as the visual features cannot sufficiently express composable actions. In this context, we propose Latent Action Composition (LAC), a novel self-supervised framework aiming at learning from synthesized composable motions for skeleton-based action segmentation. LAC is composed of a novel generation module towards synthesizing new sequences. Specifically, we design a linear latent space in the generator to represent primitive motion. New composed motions can be synthesized by simply performing arithmetic operations on latent representations of multiple input skeleton sequences. LAC leverages such synthesized sequences, which have large diversity and complexity, for learning visual representations of skeletons in both sequence and frame spaces via contrastive learning. The resulting visual encoder has a high expressive power and can be effectively transferred onto action segmentation tasks by end-to-end fine-tuning without the need for additional temporal models. We conduct a study focusing on transfer-learning and we show that representations learned from pre-trained LAC outperform the state-of-the-art by a large margin on TSU, Charades, PKU-MMD datasets.

  • 7 authors
·
Aug 28, 2023

MIS-FM: 3D Medical Image Segmentation using Foundation Models Pretrained on a Large-Scale Unannotated Dataset

Pretraining with large-scale 3D volumes has a potential for improving the segmentation performance on a target medical image dataset where the training images and annotations are limited. Due to the high cost of acquiring pixel-level segmentation annotations on the large-scale pretraining dataset, pretraining with unannotated images is highly desirable. In this work, we propose a novel self-supervised learning strategy named Volume Fusion (VF) for pretraining 3D segmentation models. It fuses several random patches from a foreground sub-volume to a background sub-volume based on a predefined set of discrete fusion coefficients, and forces the model to predict the fusion coefficient of each voxel, which is formulated as a self-supervised segmentation task without manual annotations. Additionally, we propose a novel network architecture based on parallel convolution and transformer blocks that is suitable to be transferred to different downstream segmentation tasks with various scales of organs and lesions. The proposed model was pretrained with 110k unannotated 3D CT volumes, and experiments with different downstream segmentation targets including head and neck organs, thoracic/abdominal organs showed that our pretrained model largely outperformed training from scratch and several state-of-the-art self-supervised training methods and segmentation models. The code and pretrained model are available at https://github.com/openmedlab/MIS-FM.

  • 6 authors
·
Jun 29, 2023

D-Former: A U-shaped Dilated Transformer for 3D Medical Image Segmentation

Computer-aided medical image segmentation has been applied widely in diagnosis and treatment to obtain clinically useful information of shapes and volumes of target organs and tissues. In the past several years, convolutional neural network (CNN) based methods (e.g., U-Net) have dominated this area, but still suffered from inadequate long-range information capturing. Hence, recent work presented computer vision Transformer variants for medical image segmentation tasks and obtained promising performances. Such Transformers model long-range dependency by computing pair-wise patch relations. However, they incur prohibitive computational costs, especially on 3D medical images (e.g., CT and MRI). In this paper, we propose a new method called Dilated Transformer, which conducts self-attention for pair-wise patch relations captured alternately in local and global scopes. Inspired by dilated convolution kernels, we conduct the global self-attention in a dilated manner, enlarging receptive fields without increasing the patches involved and thus reducing computational costs. Based on this design of Dilated Transformer, we construct a U-shaped encoder-decoder hierarchical architecture called D-Former for 3D medical image segmentation. Experiments on the Synapse and ACDC datasets show that our D-Former model, trained from scratch, outperforms various competitive CNN-based or Transformer-based segmentation models at a low computational cost without time-consuming per-training process.

  • 7 authors
·
Jan 2, 2022