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tags:
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- model_hub_mixin
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- pytorch_model_hub_mixin
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---
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## CellCLIP - Learning Perturbation Effects in Cell Painting via Text-Guided Contrastive Learning
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CellCLIP, a cross-modal contrastive learning framework for HCS data. CellCLIP leverages pre-trained image encoders coupled with a novel channel encoding scheme to better capture relationships between different microscopy channels in image embeddings, along with natural language encoders for repre senting perturbations. Our framework outperforms current open-source models, demonstrating the best performance in both cross-modal retrieval and biologically meaningful downstream tasks while also achieving significant reductions in computation time.
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* [Paper](https://arxiv.org/pdf/2506.06290)
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* [Github](https://github.com/suinleelab/CellCLIP/tree/main)
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## Citation
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```
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@article{lu2025cellclip,
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title={CellCLIP--Learning Perturbation Effects in Cell Painting via Text-Guided Contrastive Learning},
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author={Lu, Mingyu and Weinberger, Ethan and Kim, Chanwoo and Lee, Su-In},
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journal={arXiv preprint arXiv:2506.06290},
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year={2025}
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}
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```
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